The patch Clamp technique is used in electrophysiological studies of ion channels in tissue sections, individual living cells, or patches of the cell membrane.
Features:
Voltage clamp or current clamp technique is performed in any type of excitable cells, mostly neurons, cardiomyocytes, pancreatic beta cells, or muscle fibers.
Experiments include slice-recordings, single-cell-layer-recordings, in vivo-recordings, whole-cell-recordings, and single-channel-recordings.